Nikoletta Katsaouni

(she/her)

Postdoc

Institute for Computational Genomic Medicine

Professional Summary

I am a bioinformatics researcher working at the intersection of AI, genomics, and personalised medicine. My research focuses on developing machine-learning approaches to integrate complex biomedical data and support patient-specific prediction, therapeutic decision-making, and therapy selection.

My broader goal is to bring AI closer to truly personalised medicine — because when it comes to biology, one size rarely fits all.

Education

PhD Bioinformatics

Goethe University Frankfurt am Main

MSc Computer Science

RPTU Kaiserslautern-Landau

BSc Informatics and Telematics

Harokopio University of Athens

Interests

Machine Learning Personalised Medicine Therapeutic Prediction
Contact

Office: Haus 26, 4th floor, room 401 Goethe-University and Universitätsmedizn Frankfurt
Institute for Computational Genomic Medicine
Theodor-Stern-Kai 7
60590 Frankfurt am Main, Germany

+49 69 6301 86207
katsaouni|em.uni-frankfurt.de

Publications
Nikoletta Katsaouni, Marcel H. Schulz (2026). RANKOR: Direct Drug Prioritization from Bulk and Single-Cell Transcriptomic Signatures. Preprint (BioRxiv).
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Dennis Hecker, Xiaoning Song, Nina Baumgarten, Anastasiia Diagel, Nikoletta Katsaouni, Ling Li, Shuangyue Li, Ranjan Kumar Maji, Fatemeh Behjati Ardakani, Lijiang Ma, Zhaolong Li, Aldo Moggio, Daniel Tews, Hendrik Sager, Lars Maegdefessel, Martin Wabitsch, Johan L. M. Björkegren, Heribert Schunkert, Zhifen Chen, Marcel H. Schulz (2026). Cell type-specific epigenetic regulatory circuitry of coronary artery disease loci. Nature Communications.
DOI
Nikoletta Katsaouni, Marcel H. Schulz (2026). Hierarchical Representation Learning for Drug Mechanism-of-Action Prediction from Gene Expression Data. Preprint (BioRxiv).
URL DOI
Sebastian Cremer, Nikoletta Katsaouni, Wesley Tyler Abplanalp, Alexander Berkowitsch, Klara Kirschbaum, Michael A. Rieger, Steffen Rapp, Philipp S. Wild, Stefanie Dimmeler, Marcel H. Schulz, Andreas M. Zeiher (2023). Interaction of inherited genetic variants in the NLRP3 inflammasome/IL-6 pathway with acquired clonal hematopoiesis to modulate mortality risk in patients with HFrEF.
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Nikoletta Katsaouni, Pablo Llavona, Yascha Khodamoradi, Ann-Kathrin Otto, Stephanie Körber, Christof Geisen, Christian Seidl, Maria J. G. T. Vehreschild, Sandra Ciesek, Jörg Ackermann, Ina Koch, Marcel H. Schulz, Daniela S. Krause (2023). Dataset of single nucleotide polymorphisms of immune-associated genes in patients with SARS-CoV-2 infection. PloS One.
DOI
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