Closed
Enabling allele-specific analysis of epigenome data
Enabling allele-specific analysis of epigenome data
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At the Institute for Computational Genomic Medicine, we offer thesis projects on the intersection of computational methods and biomedical research questions. Browse the open projects below, each with a topic introduction, prerequisites, and a direct contact to the supervising researcher.
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- Contact the supervisor listed on the project page
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Open Projects
Contact the supervisor on the project page to apply.
Closed
Expanding a Nextflow pipeline for histone-association studies
Expand an existing Netxflow pipeline that links epigenome to transcriptome
Open
Expanding a Nextflow pipeline for single-cell data
Expand an existing Netxflow pipeline that links epigenome to transcriptome
Closed
Incorporating deep learning TF models into SNEEP
Adapt SNEEP with BPNet models for TF binding prediction
Open
Modifying SNEEP to account for averaged differential TF Binding
Extending SNEEP’s statistic to account for cumulative, not just maximal, TF binding effects at regulatory SNVs.
Open
Placing regulatory variants into tissue context
Map regulatory SNVs to spatial transcriptomics data
Open
Statistical analysis of liver disease transcriptomes
Study a large patient cohort of liver transcriptomes