EpiRegio

2 July 2020·
Nina Baumgarten
Nina Baumgarten
Dennis Hecker
Dennis Hecker
Marcel H. Schulz, PhD
Marcel H. Schulz, PhD
tools

EpiRegio is a resource of Regulatory EleMents (REMs), non-coding DNA regions that are predicted to regulate the expression of their target genes. It hosts 2.4 millions of such elements for the human genome and provides cell-type specific expression and activity parameters for each of the elements. It supports different searches and allows batch queries using a REST API.

Nina Baumgarten
Authors
Postdoc
I am a bioinformatician with a diverse background in analyzing genetic and epigenetic data. I have had the chance to work on a variety of projects since I joined the lab, like decoding the effect of non-coding variations, analysing GWAS data, and studying TF binding. Recently, my focus has been shifted toward spatial transcriptomics, which allows me to map genetic findings directly onto tissue architecture. I am motivated by the possibility that these data-driven insights might lead to a better understanding of complex diseases. In my free time, I love spending time in nature for hiking—it’s where the best ideas come to me!
Dennis Hecker
Authors
Postdoc
I am a biologist by training that turned into a bioinformatician for the PhD. Since starting in the SchulzLab, I have been working on analysing a variety of data and their integration with a focus on the epignome, specifically interactions between regulatory regions and genes. I also have a love-hate relationship with chromatin contact data. What keeps me going is the variety of research questions that we work on to know more about human biology and its use in medicine. I am a big fan of Python and coffee.
Marcel H. Schulz, PhD
Authors
Professor for Computational Biology
I am a Computational Biologist by education. I develop computational systems biology models and machine learning algorithms that further the understanding of gene regulation. We work on groundbreaking computational methods that enable novel approaches for personalized medicine applications in the context of different human diseases. We live and breathe open-source development.